Galapagos and Amazon basin combined

Follow in Darwin’s footsteps on Isla Santa Cruz

Day 1 in Isla Santa Cruz

Almost all visitors to the Galapagos Islands will touch down in Isla Santa Cruz at some point. From beach walks at Tortuga Bay to giant tortoises at El Chato Reserve, there is plenty to see — but make sure to visit the Charles Darwin Research Centre to learn more about the wildlife you’ll encounter on your trip.

Visit the black lava fields on Isla Santiago

Day 2 in Isla Santiago

Once a hideout for smugglers and pirates, Isla Santiago is now best-known for Sullivan Bay, where century-old lava has solidified into bubbles and caves, and Puerto Egas, a wet landing where you can see seals, sea lions and sea birds.

Take in the views on Isla Bartolomé

Day 3 in Isla Bartolomé

Tiny Bartolomé is most famous for its landscapes and scenery. A set of steep steps leads to a 360-degree viewpoint over the island, looking back on black volcanic formations, marine life and striking reds and greens.

Search for boobies on Isla Genovesa

Day 4 in Isla Genovesa

Stay with us – Isla Genovesa is also known as Booby Island due to the sheer number of goofy-looking Nazca and red-footed boobies that live here. This island is a must for bird-watching enthusiasts, with great frigatebirds, short-eared owls and many more in residence.

Head into the Amazon basin at Coca

Day 5–7 in The Amazon Basin

The starting point for most Amazon jungle trips, Coca is slowly transforming itself from tourist transport hub into somewhere worth visiting itself. Make sure to explore the riverfront and its cultural museum before journeying up the Rio Napo to the jungle.

Explore colonial Quito

Day 8–10 in Quito

The first thing you notice about Quito is that it takes your breath away.

Not in a clichéd 'look at the amazing scenery' way; it's more of a literal 'I've just stepped off the plane at three thousand metres above sea level and I feel like I've got a 30-cigarettes-a-day habit.

Squeezed between Volcán Pichincha and a cloud-shrouded mountain range which looms broodingly over the city, Quito is moulded into an elongated strip that is thin enough to cross by foot but so long it vanishes into the horizon. Almost 1.5 million people live in this strand of urban spaghetti but despite its endless suburbs, the city's gems are conveniently concentrated in the few blocks that make up the Unesco World Heritage site of Quito old town.

As the sun sets behind Pichincha, you can see the spires of the old town and beyond it a small hill, El Panecillo ('bread loaf,' so named for its odd shape) on which stands the towering Virgin of Quito looking down over the city. In the foreground runs a long strip of park linking the old town with the anarchic bustle of the new town and in the other direction, a few kilometres north of the city, is the equator and the 'Centre of the World' science museum, a favourite of hemisphere-hopping tourists.

A stroll through the old town is a lesson into the long history of war, conquest and cultural assimilation that occurred in this city ever since the Spanish arrived in South America in the mid 16th century. The original Inca city had been destroyed by civil war immediately before the conquistadors' arrival and the Spanish wasted no time in capitalising on a divided opposition. After the annihilation of the Inca empire, the city was rebuilt according to Spanish designs but by the hands of enslaved indigenous labourers, a process which produced a unique cultural fusion, the 'Quito school of art' which is still visible in the architecture and galleries of the old town.

Meanwhile, with the winds of the Inquisition in their sails, the Spanish set about converting the native population to Christianity; churches were established on the remains of sacred sites, imposing statues were built, and the gore-filled tales of the Bible were depicted in grotesque exaggeration on carvings and paintings. In the Basilica del Voto Nacional, an emaciated Jesus, face locked in agony and with blood dripping down his arms and feet, stands crucified above crowds of genuflecting indígenas. In the Monastery of Santa Catalina, paintings warn sinners of their ultimate punishment in graphic and brutal detail.

Yet despite their best efforts, the Spanish strategy of terrifying the natives into conversion only partially worked. Cultural cross-pollination touched the religious world too, blending ancient tradition with this new faith, with often spectacular results.

Outside the cocoon of the old town, the rest of Quito carries on with its daily life. Only the occasional passing of an indígena, burdened by loads that are often larger than they are, reminds you that this busy, noisy bustle is merely the latest phase in Quito's long history.